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마이펫자랑 | ADHD Medication Pregnancy: The Good, The Bad, And The Ugly

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작성자 Mack Sidhu 작성일24-07-12 16:05

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ADHD Medication During Pregnancy and Breastfeeding

The decision to stop or continue ADHD medications during pregnancy and nursing is challenging for women with the condition. There are few data regarding how exposure over time may affect the foetus.

general-medical-council-logo.pngA study recently published in Molecular Psychiatry shows that children exposed to ADHD medication in the uterus do not develop neurological disorders such as hearing or vision impairment seizures, febrile seizures, or IQ impairment. The authors acknowledge that more high-quality studies are needed.

Risk/Benefit Analysis

Pregnant women who use ADHD medications must weigh the advantages of taking them against the potential risks to the fetus. Physicians don't have the information needed to give clear guidelines, but they can provide information about benefits and risks that can aid pregnant women in making informed decisions.

A study published in Molecular Psychiatry found that women who were taking ADHD medications in early pregnancy did not have an increased risk of fetal cardiac malformations or major structural birth defects. Researchers conducted a large population-based case-control study to evaluate the incidence of major structural birth defects in babies born to mothers who had taken stimulants in the early stages of pregnancy, as well as those who had not. Clinical geneticists and pediatric cardiologists examined the cases to ensure correct classification of the cases and to reduce the possibility of bias.

The study conducted by the researchers was not without limitations. Researchers were unable to, in the first place, to separate the effects of the medication from the disorder. This makes it difficult for researchers to determine whether the small associations observed among the exposed groups were due to the use of medication or confounded by comorbidities. In addition the study did not examine the long-term outcomes of offspring.

The study did reveal that babies whose mothers had taken liquid adhd medication uk medications during pregnancy were at a slightly greater risk of being admitted to the neonatal intensive care unit (NICU) than infants whose mothers had not taken any medication or cut back on their medications prior to or during pregnancy. This increase was caused by central nervous system disorders. The increased risk of admission was not affected by the stimulant medication that was used during pregnancy.

Women who took stimulant ADHD medications during pregnancy also had a higher risk of having an emergency caesarean section or having one whose baby scored low on the Apgar scale (less than 7). These increases appear to be unrelated to the type of medication taken during pregnancy.

The research suggests that the risk of a small amount with the use of common adhd medications uk medications during the early stages of pregnancy could be offset by the greater benefits to both mother and child of continuing treatment for the woman's disorder. Physicians should speak with their patients about this and, if possible, help them improve coping skills which can lessen the effects of her disorder on her daily functioning and her relationships.

Medication Interactions

As more women than ever are diagnosed with ADHD and being treated with medication, the question of whether to continue or discontinue treatment during pregnancy is a question that doctors are having to face. Often, these decisions are taken in the absence of solid and reliable evidence regardless, so doctors must weigh their knowledge, the experiences of other doctors, and what research says on the topic as well as their own judgments for each patient.

The issue of risk to infants is extremely difficult. The research that has been conducted on this topic is based on observations rather than controlled studies and a lot of the results are contradictory. In addition, most studies limit their analysis to live births, which could underestimate severe teratogenic effects that result in abortion or termination of the pregnancy. The study that is discussed in the journal club addresses these shortcomings by analyzing both data on live and deceased births.

Conclusion A few studies have revealed an association between ADHD medications and certain birth defects however, other studies haven't shown such a relationship. The majority of studies show a neutral, or even slightly negative, effect. As a result, a careful risk/benefit analysis must be done in each case.

For many women with ADHD, the decision to stop taking medication is difficult if not impossible. In fact, in an article published in the Archives of Women's Mental Health, psychologist Jennifer Russell notes that stopping ADHD medication during pregnancy can increase depression, feelings of isolation and family conflict for these patients. A decrease in medication could also impact the ability to drive safely and to perform work-related tasks which are vital aspects of normal life for those suffering from ADHD.

She suggests women who are uncertain about whether to continue or discontinue medication due to their pregnancy consider the possibility of educating friends, family members and colleagues on the condition, its impact on daily functioning, and on the advantages of continuing the current treatment regimen. In addition, educating them Can You Get Adhd Medication Without A Diagnosis Uk help the woman feel supported when she is struggling with her decision. It is important to note that certain medications are able to be absorbed through the placenta so if the patient decides to stop taking her ADHD medication during pregnancy and breastfeeding, she must be aware of the possibility that traces of the medication could be passed on to the baby.

Risk of Birth Defects

As the use and abuse of ADHD drugs to treat symptoms of attention deficit disorder hyperactivity disorder (ADHD), increases as does the concern about the possible effects of the drugs on foetuses. Recent research published in the journal Molecular Psychiatry has added to the body of knowledge on this issue. Researchers utilized two massive datasets to analyze over 4.3 million pregnancy and determine whether stimulant medications caused birth defects. While the overall risk is low, the researchers did find that first-trimester exposure to ADHD medicines was associated with an increased risk of certain heart defects, such as ventriculoseptal defect (VSD).

The researchers behind the study found no connection between the use of early medications and congenital abnormalities such as facial clefting or club foot. The results are in line with previous studies that have shown the presence of a small, but significant increase in the risk of developing cardiac malformations among women who began taking ADHD medications prior to the time of pregnancy. The risk grew in the latter half of pregnancy, as many women begin to discontinue their ADHD medication.

Women who used ADHD medications during the first trimester of pregnancy were also more likely to undergo caesarean sections, a low Apgar score after delivery and a baby who required breathing assistance during birth. However the researchers of the study were unable to eliminate selection bias by restricting the study to women who didn't have any other medical issues that could have contributed to these findings.

The researchers hope their research will help inform the clinical decisions of doctors who treat pregnant women. They advise that while a discussion of the risks and benefits is crucial however, the decision to stop or keep treatment must be based on each woman's needs and the severity of her ADHD symptoms.

The authors caution that, while stopping the medication is a possibility to consider, it is not recommended because of the high incidence of depression and mental health issues among women who are pregnant or recently gave birth. Additionally, research suggests that women who stop taking their medications will have a harder transitioning to life without them once the baby is born.

Nursing

It can be a stressful experience to become a mother. Women suffering from ADHD can face severe challenges when they must deal with their symptoms, attend doctor appointments, prepare for the birth of their child and adjust to new routines. Many women choose to continue taking their ADHD medication during pregnancy.

The risk to nursing infant is low because the majority of stimulant medication passes through breast milk in low amounts. However, the rate of exposure to medication by the newborn can vary depending on dosage, frequency it is taken and the time of day it is administered. In addition, individual medications enter the baby's system differently through the gastrointestinal tract and breast milk and the impact of this on a newborn isn't yet fully understood.

Because of the lack of research, some doctors might be tempted to stop taking stimulant medications during the pregnancy of a woman. This is a complicated decision for the patient, who must balance the benefits of continuing her medication against the potential dangers to the fetus. In the meantime, until more information is available, GPs may inquire about pregnant patients whether they have any history of ADHD or if they intend to take medication during the perinatal phase.

Many studies have shown that women can continue taking their ADHD medication safely during pregnancy and while breast-feeding. This has led to an increasing number of patients opt to do this and, after consulting with their doctor, they have discovered that the benefits of maintaining their current medication outweigh any potential risks.

Women who suffer from ADHD who plan to breastfeed should seek advice from a specialist psychiatrist prior to becoming pregnant. They should discuss their medication with their physician and discuss the pros and cons of continued treatment, including non-pharmacological management strategies. Psychoeducation is also required to help pregnant women suffering from ADHD recognize the signs and underlying disorder. They should also be educated about treatment options and reinforce coping mechanisms. This should involve an approach that is multidisciplinary, including the GP as well as obstetricians, psychiatry and obstetricians. Pregnancy counseling should include discussion of a treatment plan for the mother and child, monitoring of signs of deterioration and, if needed, adjustments to the medication regime.
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